The show focuses on a trio of strangers with a shared interest in true crime podcasts, who become friends while investigating a succession of suspicious murders in the Arconia, their upscale apartment building on Manhattan's Upper West Side, and producing their own podcast about the cases, titled Only Murders in the Building. Its five seasons premiered on Hulu in August 2021, June 2022, August 2023, August 2024, and September 2025. In October 2025, the series was renewed for a sixth season which is slated to premiere on December 8, 2026.